OBJECTIVE Previously published research examining the effects of high egg consumption in people with type 2 diabetes mellitus (T2DM) has produced conflicting results leading to recommendations to limit egg intake. However, people with T2DM may benefit from eggs because they represent a nutritious and convenient way of improving protein and micronutrient content of the diet, which has value for satiety and weight management. This randomised, controlled study aimed to determine whether a high egg diet (2 eggs/day on 6 days/week) affected circulating lipid profiles and, in particular, high-density lipoprotein cholesterol (HDL-C), in overweight or obese people with pre-diabetes or T2DM, when compared to a low egg diet (< 2 eggs/week). RESEARCH DESIGN AND METHODS 140 subjects were randomised to either a high or low egg diet as part of a three month weight maintenance study. Subjects attended the clinic monthly and were instructed on the specific types of foods and quantities to be consumed. RESULTS There was no significant difference in the change in HDL-C from screening to three months between groups; the mean difference (95% confidence interval (CI)) between the high and the low egg group was +0.02 mmol/L (-0.03, 0.08); p=0.38. There was a within-group trend towards an improvement in HDL-C in the high egg group: +0.03 mmol/L (95% CI: -0.00, 0.07); p=0.07. No between-group differences were found for total cholesterol, low-density lipoprotein cholesterol, triglycerides, or glycaemic control. While both groups were matched for protein intake, the high egg group reported less hunger and greater satiety post breakfast. CONCLUSIONS High egg consumption did not have an adverse effect on the lipid profile of people with T2DM, who are at higher risk of cardiovascular disease. This study suggests that a high egg diet can safely be included as part of the dietary management of T2DM and may provide greater satiety.