Wednesday, 27th August Australian Diabetes Society and the Australian Diabetes Educators Association Annual Scientific Meeting 2014

“The HBA1c Balancing act” – Medical Nutrition Therapy and Lifestyle InterventionSpeaker: Geraldine Georgeou, Accredited Practising Dietitian“The HBA1c Balancing act” tips on how to encourage the patients through holistic diabetes management program including a focus on “medical nutrition therapy” to support blood glucose management.The session will consist of discussion of supporting blood glucose management and improving health outcomes through Lifestyle intervention, including medical nutrition therapy (MNT). The session will see the outcomes of the “Look AHEAD Trial” - which explores 5145 patients that underwent intensive lifestyle intervention that also included the use of MNT, showed their status of HbA1C, cardiovascular risk factors, and weight improved over a 4-year period.

"Beyond Low Glucose Suspend: Progressing towards closing the loop"Speaker: Francine R Kaufman, Chief Medical Officer and VP of Global Medical and Clinical Health Affairs, Medtronic DiabetesIn 2009, Medtronic introduced the Low Glucose Suspend feature in our insulin pumps, representing the first step in the roadmap toward an artificial pancreas. As we approach our next step, we would like to introduce you to Predictive Low Glucose Management technology. This technology is designed to halt insulin delivery when the user’s glucose trend is predicted to pass below their low glucose threshold and will automatically resume when the glucose level is predicted to return to target threshold. This represents our most advanced breakthrough in glucose control as well as our dedication towards making the artificial pancreas a reality.Our guest speaker, will be introducing Predictive Low Glucose Management and offering practical tips/best practices for managing pump patients. They will also be sharing their expertise and fresh perspective in type 1 diabetes management with insulin pumps and continuous glucose monitoring.

"Continuous Glucose Re absorption & the Cycle of Glucose Toxicity"

Speaker: Prof Ele Ferrannini, University of Pisa, Italy

It is well established that chronic hyperglycaemia contributes to impaired insulin secretion and insulin resistance. An integrated physiological response is generated due to forced reduction in blood glucose concentrations due to  anti-hyperglycaemic agents. This session will focus on the adaptive changes undergone by the body to pharmacologically-induced changes in blood glucose levels. 

"Getting to the heart of the matter - Developments in the diagnosis and treatment paradigms for type 2 diabetes"

Speakers: 
Professor Mark Cooper, Baker IDI Heart & Diabetes Institute
Professor Henry Krum, Director Centre of Cardiovascular Research & Education in Therapeutics, Monash University, Melbourne

With the ever changing landscape of Type 2 Diabetes (T2D) diagnosis and management, this talk will provide insights into current T2D issues, including use of HbA1c in diagnosis and current treatment options in T2D. Prof Cooper will address the recent changes in the PBS reimbursement restrictions in T2D as well as provide insights in the benefits of combination therapy in T2D.

Professor Krum will talk about CV issues in T2D, providing an update on the latest CV outcomes trials evaluating the CV safety of DPP-4 inhibitors. Including, the important, and perhaps somewhat overlooked issue of heart failure in T2D and the associated risk factors.

Carolyn Briggs, Senior Elder of the Boon Wurrung Foundation
Welcome to Country

Georgie Crozier MLC; Parliamentary Secretary of Health
Conference Opening

Jenny Gunton and Tracy Aylen
Welcome from ADS & ADEA Presidents

*Recorded Session*

*GP CME Eligible Session*

• Pipeline blood glucose-lowering therapies - Ele Ferrannini
• Novel therapies for type 2 diabetes - Timothy Davis
• DPP-4i/GLP-Ra - John Prins
• TBC - Stephen Colagiuri

• Hospital-wide HbA1c measurement identifies undiagnosed diabetes in 5% of patients aged 54 years and over: results of the Austin Health Diabetes Discovery Initiative - Natalie Nanayakkara
• Routine HbA1c measurement identifies undiagnosed diabetes in 20% of general medical inpatients with an HbA1c ≥ 6.5%: results of the Austin Health Diabetes Discovery Initiative  - Natalie Nanayakkara
• Higher estimated glomerular filtration is associated with insulin resistance in healthy, non-diabetic humans, independent of adiposity - JASMINE G LYONS
• Adverse glycaemic events and lack of treatment escalation: time for hospital action - Spiros Fourlanos
• DIABETES ACROSS THE DITCH: WINNING BATTLES BUT LOSING THE WAR? - Paul L DRURY
• Greater length of hospital stay in diabetes inpatients: 2002-2013 - Peter G Colman
• Trends in blood glucose levels and management of diabetes in 467,955 patients in primary care in Australia from 2005 to 2013 - Neale Cohen
• Glucose Management in a Cluster Randomized Trial of Evidence-Based Treatment Protocols for Acute Stroke (QASC) - N Wah Cheung

• Understanding the physiological and biochemical causes of high-fat diet induced defects in hepatic glucose metabolism - Greg M Kowalski
• Protein kinase C epsilon deletion in adipose tissue, but not in liver, modulates fatty acid mobilisation and hepatic insulin action - Carsten Schmitz-Peiffer
• Protein kinase D regulates hepatic glucose metabolism in vitro and in vivo - Amanda J Genders
• Unique changes in hepatic sphingolipid species after high-fat feeding in BALB/c mice correlate with protection from diet-induced glucose intolerance - Magdalene K. Montgomery
• Hepatic FoxO1 acetylation is involved in oleanolic acid-induced memory of glycemic control - Xiu Zhou
• DPP4 and FAP in glucose and lipid metabolism and liver injury in mice - Mark D Gorrell
• Characterisation of the Adiponectin Receptors: Palmitoylation of AdipoR1 and AdipoR2 is Required for Efficient Cell-Surface Expression and Down-Stream Signalling. - Sahar Keshvari
• Acute administration the IL-6-CNTF chimera IC7 improves glucose tolerance via suppression of hepatic gluconeogenesis - Tamara L Allen

*Recorded Session*

• Dissecting the genetic basis of inherited adrenocortical failure - Adrian Clark

*Recorded Session*

• Transforming Diabetes Care: A Sacred Trust - Teresa Pearson

• Mineralocorticoid receptors: cardiac fibrosis, metabolism and inflammation - Morag Young
• New insights into signaling at the glucagon-like peptide-1 receptor - Patrick Sexton
• The melanocortin 2 receptor accessory proteins - Adrian J.L Clark

*Recorded Session*

• Diabetes distress and depression: facing challenges, bringing solutions - Jane Speight

*GP CME Eligible Session*

• Self tracking, social networking and the rise of citizen science in health  - Kathleen Gray
• Use of Telemedicine in the Management of Diabetes - Anthony Russell
• How E-Health Affects the Way Patients and Consumers Make Decisions and Manage Their Health - Annie Lau
• Smartphone technology satisfaction and usefulness study for improved self management in type 1 adults  - Veronica Mills
• A DIABETES TECHNOLOGY NURSE MAKES A DIFFERENCE AT AUSTIN HEALTH - Victoria Stevenson

*Recorded Session*

• Implementing and utilizing the Biogrid Database in Diabetes Centres - Peter Colman
• Management of Diabetes in the General Care Setting Update - Giuliana Murfet
• Australian National Diabetes Audit- Australian Quality Clinical Audit 2013  - Sophia Zoungas
• NADC accreditation - Elaine Pretorius
• NADC Q&A session - Natalie Wischer

• Relationship and Engagement, a Perfect Partnership with your CDE - Lorraine Pitman
• Centralised Team Model Embedded In General Practice - Dianna Fornasier
• The USA Experience  - Teresa Pearson
• New Gadgets for CDEs - Rachel McKeown

• Mitochondria Hormesis and Diabetic Nephropathy: A New Paradigm - Kumar Sharma
• Pathological Cardiolipin Remodeling by ALCAT1 Controls Mitochondrial Etiology of Diabetic Complications - Roger Shi
• Monogenic causes of mitochondrial disease and their impact on metabolism - David Thorburn
• Disturbed mitochondrial homeostasis and diabetic nephropathy: are we any closer to a targeted therapy? - Melinda Coughlan

• Detangling insulin and glucose and the mind: brain structure, function and incident dementia in the Sydney Memory and Ageing Study. - Katherine Samaras
• The effects of statin use and metabolic syndrome on cognitive decline in the elderly: the Sydney Memory and Ageing Study. - Katherine Samaras
• Preventing double jeopardy: diabetes and obesity risk minimization in youth with severe mental illness receiving antipsychotic medications. The Keeping the Body in Mind Program. - Katherine Samaras
• Depression symptom clusters differentially predict cardiovascular hospitalisation in people with type 2 diabetes - Giesje Nefs
• Associations between depression, motivation, and physical activity in adults with type 2 diabetes: Results from the Diabetes PACT Study - Kylie Mosely
• Evidence of greater impact of diabetes complications on the mental health of Asian immigrants:a hidden co-morbidity - Margaret McGill
• SUICIDAL IDEATION AND SELF-HARM IN TYPE 1 AND TYPE 2 DIABETES: RESULTS FROM DIABETES MILES - AUSTRALIA - Tonelle Handley
• Schizophrenia is an independent risk factor for all-cause mortality in type 2 diabetes: The Fremantle Diabetes Study - Wendy A Davis

Terminals for viewing the e-posters are provided in the exhibition hall.  A complete listing of e-posters can be found later in the program and on the smart phone/mobile device ‘app’.

• Connect2: A motivational peer support model for people with type 2 diabetes - Udani Abeypala
• Diabetes SA Workshop - Transition and Type 1 Diabetes - Kerryn Boogaard
• ‘I wish they could be in my shoes’: Consumer insights into tertiary diabetes care. - Jacqueline Cotugno
• Profile of a tertiary diabetes clinic for young adults focusing on psychosocial assessment - Thomas Dover
• Who's Calling the Shots?: How much do young people with Type 1 Diabetes know about managing their diet? - Catherine Forbes
• Diabetes Mellitus and the risk of Primary Open angle glaucoma - POONAM LAVAJU
• An overnight Closed Loop Study at home in People with Type I Diabetes – The experience of a Diabetes Nurse Educator working as a Research Co-ordinator. - Margaret Loh
• Type 1 Clinic- The Move Towards Social Media and Technology - Elizabeth O'Meara
• New Zealand Managed Roll Out of Diabetes Nurse Specialist Prescribing. - Helen J Snell
• Hospital Wide Roll-out of Safety Pen Needles for Insulin Delivery Devices – A new Diabetes nurse educator’s experience - Tess Amoore

• Role of adipose tissue in the pathogenesis of non-alcoholic steatohepatitis (NASH) in high fat fed foz/foz mice - Tenzin Dagpo
• The Effects of Diabetes and Pregnancy on Tumour Necrosis Factor-alpha Receptors 1 and 2  - Jas-mine Seah
• Analysis of the RAPID Signature in a Longitudinal Cohort at High Risk of Type 1 Diabetes - Ryan J Farr
• Quercetin and quinic acid synergistically downregulates inflammatory response in the liver and kidney of lipopolysaccharide-induced rats: Targeting diabetes and inflammation - Aditya Arya
• Oral Iron Chelation by Deferasirox (DFS) Does Not Impact the Autoimmunity of Type 1 Diabetes and Blood Collection Associates with Decreased Incidence of Diabetes. - Amit Lalwani
• ALLELE FREQUENCY DIFFERENCES FOR THE GENE MTNR1B IN YOUNG SOUTH ASIANS WITH ELEVATED POST-MEAL INSULIN. - Maria A Matuszek
• An intervention study of berberine effecting on gut microbiota, enterogenous endotoxin and related signal molecular about endotoxin in liver to the obese rats with insulin resistance  - Zhao Tieyun
• Coronary Heart Disease risk factors: How much do University students in United Arab Emirates know about it? - Nelofer Khan
• Knowledge of signs and symptoms of coronary heart disease among University students in United Arab Emirates - Nelofer Khan

• The persisting proinflammatory effects of transient glucose exposure are equivalent to that observed in chronic hyperglycemia with diabetes - Chris Tikellis
• Increased MMP-9 activities in a diabetic sterile wound model are partially prevented by insulin treatment - Taria Shin Yi Ng
• Novel miRNA-21 pathway interactions reveal coordinated and cooperative regulation of important fibrotic genes - Aaron D McClelland
• INTERACTIONS BETWEEN GLUCAGON-LIKE PEPTIDE-1 (GLP-1) AND THE RECEPTOR FOR AGES (RAGE) IN DIABETIC NEPHROPATHY - Karly Sourris
• LATE-INTERVENTION STUDY WITH EBSELEN IN AN EXPERIMENTAL MODEL OF TYPE 1 DIABETIC NEPHROPATHY - Sih Min Tan
• Dicarbonyl stress in the absence of hyperglycaemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes. - Raelene Pickering
• MITOCHONDRIAL TARGETING OF SUPEROXIDE BY MITOQ IMPROVES METABOLIC RENAL DYSFUNCTION. - Micheal S Ward
• Analyzing PKA signaling in adipose depots - Barton Wicksteed
• Characterisation of the glycosylation pathway required for the efficient secretion of HMW adiponectin - Julie Webster
• Using RNA-Seq to Characterise Adipogenic Networks - Jingjing He
• The role of SEIPIN in adipogenesis and lipid droplet expansion - H. Robert Yang
• The Pro-fibrotic Protein CCN2 Upregulates Uncoupling Protein-1 in Pre-adipocytes: Implications for Dietary-Regulated Thermogenesis. - Stephen M. Twigg
• L-5F and D-4F apolipoporotein A-I mimetic peptides suppress hepatic inflammation and improve insulin sensitivity - Kristine C-Y McGrath
• Perilipin-5 facilitates fatty acid oxidation and inhibits excessive triglyceride secretion in the liver. - Stacey N Keenan
• The role of perilipin 5 (PLIN5) in muscle lipid and glucose metabolism in cell systems - Ruzaidi Azli Mohd Mokhtar
• Cholesterol as a key factor in the development of NAFLD in high fat fed mice - Songpei Li
• PPARα–mediated ER stress in the liver is associated with the suppression of autophagy pathway - Eunjung Jo
• Effects of elevated fatty acids and/or glucose on glucose metabolism pathways in human trophoblasts - Carina Bertoldi Franco
• Deletion of SIRT1 specifically in skeletal muscle of mice does not alter body weight, fat mass or glucose tolerance under normal, fasting or high fat feeding conditions. - Amanda E Brandon
• Amelioration of diet-induced insulin resistance in rats by a single glucose meal - Holly Johnson
• The nuclear receptor Nor-1 is a target of exercise signalling in skeletal muscle and mediates exercise-associated metabolic phenotypes - Michael A Pearen
• Changes in glycogen structure over feeding cycle sheds new light on blood-glucose control - Mitchell A Sullivan
• Angiotensin II Impairs Insulin’s Actions in Skeletal Muscle of High- but not Normal-Sodium Fed Rats - Steve Rattigan
• Insulin sensitivity differences using surrogate markers in fat depots of high fat fed obese mice - Babu Raja Maharjan
• Deletion of the pro-apoptotic BH3-only protein Bim results in increased islet size in a mouse model of type 2 diabetes - Jingjing Ge
• The role of cell polarity in controlling insulin secretion. - Wan Jun Gan
• Sodium glucose co-transporter 2 is not expressed in rat pancreatic islets. - Christos N Joannides
• Deletion of the selenoprotein SEPS1 in β-cells leads to impairment in insulin secretion - Steve Weng
• Cytokine-induced Gene Expression in the Insulin-Secreting Liver Cell Line: Melligen cells - Ann M Simpson
• Islet α-cell specific gene expression - Barton Wicksteed
• NOD^k mice develop obesity, hyperinsulinaemia and severe hyperglycaemia when fed a high fat diet- a new murine model of type 2 diabetes - Ainy Hussain
• High dietary iron synergises with high fat feeding in causing acute pancreatitis in Sprague-Dawley rats - Ayumi Hosaka
• ­Phenotypic Changes Of Tissue Macrophage Populations In Mouse Models of Diabetes and Obesity - Rebecca Seehoo
• Understanding a bugs’ life in the fat land:  Gut microbiome, obesity and Diabetes - Anandwardhan A Hardikar
• Gut microbiota and microRNAs: The micromanagerial network in diabetes and obesity. - Holly Kristensen
• Human Islet-derived Progenitor Cells regulate T cell proliferation via exosomal transfer of microRNAs - Mugdha Joglekar

• ASSISTING GENERAL PRACTITIONERS TO MANAGE TYPE 2 DIABETES PATIENTS IN THE PRIMARY CARE SETTING. - Samantha M Bridgland
• Suicidal ideation or non-suicidal self-harm? A mismatch between the DSM-IV criterion and PHQ-9 item nine - Jessica L Browne
• Objective Perimetry in Diagnosing Early Retinopathy in Type II Diabetes - Rong Hui Chia
• Information Handbook on Insulin Pump Therapy: A Novel Presentation to Insulin Pump Information - Deb Foskett
• Hypoglycaemic presentations - are they slipping through the net? - Emma Holland
• Evaluation and review of an NDSS pregnancy resource for women with type 1 and type 2 diabetes - Effie Houvardas
• Models of care and relational coordination between health professionals involved in insulin initiation for people with type 2 diabetes: An exploratory survey - Jo-Anne Manski-Nankervis

*Recorded Session*

• TBC - Rury Holman

14:00 Introduction 

S Andrikopoulos

14:05 The art of scientific writing 

P Ebeling 

14:20 The peer review process 

D Wilhelm

14:35 Responding to reviewer comments 

J Greenfield

14:50 Publishing ethics: Fabrication, Falsification and Plagiarism 

A Clark

15:05 Questions and discussion

*Recorded Session*

• Cross-talk between insulin resistance and ß-cell dysfunction in type 2 diabetes : clinical implications - Ele Ferrannini

Villain - Timothy Noakes, Troy Stapleton & Ron Raab

Victim - Gary Kilov,Nicole Kellow & Bill Shrapnel

*Recorded Session*

*GP CME Eligible Session*

• Impact of Specialised Inpatient Diabetes Service on Hospital Stay and Complications - Sharon Yeoh
• Utility of Lower Serum Fibroblast Activation Protein in the Exclusion of Clinically Significant Liver Fibrosis Due to Non-alcoholic Fatty Liver Disease in Diabetes and Obesity. - Kathryn Williams
• Access to a Transition Diabetes Service for Young Adults with Type 1 Diabetes (T1DM) Reduces Frequency and Length of Stay of Diabetic Ketoacidosis (DKA) Admissions. - Kharis Burns
• Incident glucose disorders and all-cause mortality at 15 years in treated HIV-infection. - Chelsea N McMahon
• THE IMPACT OF EXERCISE ON THE FALL IN PLASMA INSULIN FOLLOWING REDUCTION OF BASAL INSULIN PUMP INFUSION RATES IN PEOPLE WITH TYPE 1 DIABETES - Sybil A McAuley
• Relationship between NT-proBNP with 24-hour haemodynamic parameters in patients with diabetes - Renata Libianto
• Mortality trends among type 1 and type 2 diabetes in Australia 2000-2010 - Jessica Harding
• Gestational Diabetes Mellitus in the first trimester: Evidence for poor neonatal outcomes despite treatment  - Arianne N Sweeting

*Recorded Session*

• An update on changes to the HbA1c - George Barker
• Management of Diabetes; HbA1c or BMI ? That is the question - Nic Kormas
• BIG FOOT. Assessing the feet and footwear of obese patients with diabetes when recommending an increase in weight-bearing activity - Anna Crawford
• tbc - Dianne Bennett

• Sorcs1: from diabetes QTL to cellular function - Alan Attie
• Defining Networks of Interacting Genetic Variants that Contribute to Type 1 Diabetes, Type 2 Diabetes and Diabetes Complications - Grant Morahan
• The use of Systems Biology to study Metabolic Disease - David James
• Macronutrient balance and the geometry of metabolism - Stephen Simpson

• Continuous Subcutaneous Insulin Infusion (CSII) in Children and Young People with Type 1 Diabetes( TID) commenced at Diagnosis Compared to those who Commenced CSII one year or more after Diagnosis - Deb Foskett
• Keeping adolescents with diabetes engaged with specialist diabetes services - Alison R Lancaster
• Normalization of blood glucose levels following Islet cell transplantation (ITx) for unstable type 1 diabetes mellitus (T1DM) - Kathy M Howe
• Helping young people through transition.  Results from the NDSS Youth Transition Pack (YTP) Evaluation - Renza Scibilia
• Reproductive health knowledge, attitudes and beliefs in young women with Type 1 Diabetes Mellitus (T1DM) aged 15 – 25 years attending a tertiary centre multidisciplinary transition clinic. Indications for diabetes education. - Dr Jesuina Noronha
• Structured type 1 diabetes education delivered in routine care reduces diabetes-related emergencies and emotional distress: results from OzDAFNE - Elizabeth Holmes-Truscott
• DIABETES AT SCHOOL – WORKING TOWARDS CONSISTENCY - Karen Crawford
• A NEW PAEDIATRIC MODEL OF CARE TAKES DIABETES OUT OF HOSPITAL TO THE HOME AND COMMUNITY - Lea Sorensen

• Differential Intrarenal Innervation in Hypertensive and Diabetic Rodents - Anna Watson
• THE EFFECT OF C21 ON DIABETICS NEPHROPATHY PROGRESSION VIA AT2R ACTIVATION - Bryna SM Chow
• Transgenic expression of dominant-active IDOL in liver: A novel  mouse model of hypercholesterolaemia and atherosclerosis    - Anna C Calkin
• Diabetes Increases Reticulated Platelets due to Enhanced Proliferation and Expansion of Bone Marrow Megakaryocyte Progenitors. - Andrew J Murphy
• Administration of Monomeric Amyloid β₄₂ Alters Energy Metabolism And Induces Cardiac Dysfunction in Mice - Juliane K Czeczor
• Sitagliptin is more effective than Gliclazide in Preventing Pro-Fibrotic and Pro-Inflammatory Gene Expression Changes in a Rodent model of Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) - Jing Ren
• The Role of Nox4 in the Diabetes Associated Atherosclerosis Development - Stephen P Gray
• New diabetes drug targets from structural characterization of liver glycogen - Robert G Gilbert